Protein name:
Immunoglobulin superfamily member 1 (IgSF1) ;
Alternative:
Inhibin-binding protein (InhBP) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with INHA; the interaction is not confirmed by standard receptor binding assays. Interacts with ACVR1B; the interaction appears to be ligand-dependent as it is diminished by inhibin B and activin A. Interacts with ACVR2A, ACVR2B, ACVRL1 and BMPR1B (By similarity). Interacts with HECTD1.
Function:
Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription.
Subcellular Location:
Isoform 3
Secreted
Protein Attributes:
50:
MMLRTFTLLL | LCIWLNRGMT | SMAAVESQPE | LWIESNYPQA | PWENITLWCK |
100:
SPSRVSSKFL | LLKDNTQMTW | IHPPYKTFQV | SFFIGALTES | NTGLYRCCYW |
150:
NEKGWSKPSK | ILELEAPGQL | PKPIFWIQAE | TPPFPGCNVN | ILCHGWLQDL |
200:
VFMLFKEGYT | EPIDYQVPTG | TMAIFSIDNL | APENEGIYIC | RTHIQMLPTL |
250:
WSEPSNPLKL | VVAGLYPKPT | LTAHPGPILA | PGESLSLRCQ | GPIYGMTFAL |
300:
MRLEDLKKPY | YYKKPIKNEA | YFYFQALKTQ | DTGHYLCFYY | DGSYRGSLLS |
350:
DILKIWVTDT | FPKTWLLVQP | SPVIQMGQNV | SLRCGGLMDG | VGLALHKKGE |
400:
EKPLQFLDAT | SNTGNNSFFL | KNVTYRDAGI | YSCHYYLTWK | TSIKMATYNT |
450:
VELIVVAWPS | SVFKVGKTIT | LQCRVSHPVL | EFSLEWEETT | TFQKFSVDGD |
500:
FIITNIEGQG | TGTYSCSYRI | ESHANIWSHR | SEPLKLVGPA | VTGFLPWNSI |
550:
LNEAIRVSLT | VQFLSLLLLV | LWLQWKCRRL | RLREAWLLGT | AQGVAMLVIL |
600:
IALLCCGLCN | GALTEEIEII | MPTPKPELWA | ETNFPQAPWK | NVTLWCRSPS |
650:
GSTKEFVLLK | DGTGWIATRP | ASEQVRAAFP | LGALTQSHTG | SYHCHSWEEM |
700:
AVSEPSEALE | LVGTDILPKP | VISASLPIRG | QELQIRCKGW | LEGLGFALYK |
750:
MGEQEPVQQL | GAVGREAFFT | IQRMEDKEEG | NYSCRTHTEK | QPFKWSEPSA |
800:
PLELVIKELY | PKPFFKTWAS | PVVTPGSRVT | FNCSTSREHM | SFILYKDGNE |
850:
IASSDPVWGN | PGTSTAHFLI | ISVGIGDGGN | YSCRYYDFSI | WSEPSDPVEL |
900:
IVTEFYPKPT | LLAQPGPVVL | PGKNVTLRCQ | GIFQGMRFAL | LQEGAHAPLQ |
950:
FQSASGTSVD | FLLHTVGAED | FGNYSCVYYE | TTMSNRGSYL | STPLMIWVTD |
1000:
TFPRPWLSAE | PSSVVTMGQN | VTLWCQGPVH | GVGYILHKEG | EATSMQLWDS |
1050:
TSNEGAFPII | NISGASIGRY | SCCYHPDWMS | PIKIQPSNTL | ELIVTGLLPK |
1100:
PSLLVQPGPM | VVPGENMTFQ | CQGELPDSTF | VLLKEGTQQP | IEQQRPSGYR |
1150:
ADFWMPVVRD | QDSGVYSCVY | YLDSAPLVAS | NHSNSLEIWV | TDKPPKPSLS |
1200:
AWPSTVFKLG | KDITLQCRGP | LPGVEFVLEH | DGEEAPQQFS | EDGDFVIGNM |
1250:
EGKGIGNYSC | SYRLQAYPDI | WSEPSDSLEL | VGAAGPVAQE | CTVGNIVRST |
1300:
LIVVVVVALG | IVLAIEWKKW | PRLRTRGSET | DGRDQTIVLE | ECNQDGEPGT |
1320:
ATNSPSSALQ | GVSVEQTVPI |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Polyclonal Antibody for Rat IgSF1
Polyclonal Antibody for Rat IgSF1
Polyclonal Antibody for Rat IgSF1
Monoclonal Antibody for Rat IgSF1
Monoclonal Antibody for Rat IgSF1
Monoclonal Antibody for Rat IgSF1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
tissue :
Pituitary .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY